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HEPARIN-INDUCED
THROMBOCYTOPENIA
Fourth Edition
Abridged Special Edition
Edited by
Theodore E. Warkentin
Michael G. DeGroote School of Medicine, McMaster University
Hamilton Regional Laboratory Medicine Program
Hamilton, Ontario, Canada
Andreas Greinacher
Ernst-Moritz-Arndt-University-Greifswald
Greifswald, Germany
Informa Healthcare USA, Inc.
52 Vanderbilt Avenue
New York, NY 10017
© 2007 by Informa Healthcare USA, Inc.
Informa Healthcare is an Informa business
No claim to original U.S. Government works
Printed in the United States of America on acid-free paper
10987654321
International Standard Book Number-10: 1-4200-6897-0
International Standard Book Number-13: 978-1-4200-6897-9
This book contains information obtained from authentic and highly regarded sources. Reprinted
material is quoted with permission, and sources are indicated. A wide variety of references are
listed. Reasonable efforts have been made to publish reliable data and information, but the author
and the publisher cannot assume responsibility for the validity of all materials or for the
consequence of their use.
No part of this book may be reprinted, reproduced, transmitted, or utilized in any form by any
electronic, mechanical, or other means, now known or hereafter invented, including photocopying,
microfilming, and recording, or in any information storage or retrieval system, without written
permission from the publishers.
For permission to photocopy or use material electronically from this work, please access www.
copyright.com (http://www.copyright.com/) or contact the Copyright Clearance Center, Inc.
(CCC) 222 Rosewood Drive, Danvers, MA 01923, 978-750-8400. CCC is a not-for-profit organiza-
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Contents
Contributors
iv
1.
Clinical Picture of Heparin-Induced Thrombocytopenia
1
Theodore E. Warkentin
2.
Treatment of Heparin-Induced Thrombocytopenia: An Overview
47
Andreas Greinacher and Theodore E. Warkentin
3.
Danaparoid for the Treatment of Heparin-Induced Thrombocytopenia
83
Beng Hock Chong and Harry N. Magnani
iii
Contributors
Beng Hock Chong
St. George Hospital and University of New South Wales, Kogarah,
New South Wales, Australia
Andreas Greinacher
Ernst-Moritz-Arndt-University-Greifswald, Greifswald, Germany
Harry N. Magnani
Medical Consultant, Oss, The Netherlands
Theodore E. Warkentin
Michael G. DeGroote School of Medicine, McMaster University,
and Hamilton Regional Laboratory Medicine Program, Hamilton, Ontario, Canada
iv
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